Vetoquinol Zylkene Calming Supplement, 225mg for Dogs and Cats 23-65 lbs., Front Hover to Zoom

Vetoquinol Zylkene Calming Supplement, 225 mg for Dogs 23-65 lbs.

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Key Benefits

  • Clinically proven to help relieve stress without drowsy side effects
  • Vet recommended to help pets cope with challenging situations like thunderstorms, car rides, separation, and more
  • Made with natural ingredients that are easy on sensitive stomachs with a lactose- and preservative-free formula
  • The only brand to contain alpha-casozepine, a naturally occurring milk protein found in cow’s milk


A pet’s life is full of new people, new situations, and new challenges. With Zylkene®, your pet can find balance when life gets stressful.

Zylkene is a behavior supplement that helps dogs and cats relax, adapt to new locations, or cope with challenging situations — without making them drowsy.

When to use Zylkene:

  • New places. Whether your pet is visiting the groomer, the vet, or moving to a new home with you, Zylkene can help them stay calm as they adjust to new environments without modifying their behavior or making them drowsy.
  • New situations. Fireworks, thunderstorms, and travel: few things are more stressful to your pets. That’s why Zylkene is the perfect supplement to help pets stay calm without sedation, which makes new situations easier for them — and for you.
  • New people. Is company coming over? Do you have a new baby in the house? With Zylkene, your pets can calmly adjust to new additions to the family — or just friends coming over to visit – without stressing out about it.

Zylkene can be given whole or opened at meal time and can be used for short- or long-term use. It’s the perfect supplement to help your pet face life’s challenges.

Vetoquinol stands behind its products with a 100% sastifaction guarantee or your money back. Try it today!


Hydrolized milk protein (bovine) providing alpha-casozepine, FD&C blue #1 (capsule), hypromellose (capsule), magnesium stearate, maltodextrin, titanium dioxide (capsule)


Zylkene 225 mg is made for dogs 23 to 65 pounds.

23-32 lbs and under: 1 capsule/day
33-65 lbs: 2 capsules/day

Capsules can be administered orally as a single dose, whole or opened at meal time. Use as recommended by your veterinarian. Short-term use: Use Zylkene for 1–2 days before a planned event or change in environment. Some animals may need earlier administration (5–7 days).

Product Info

Zylkene 225 mg is available in 14-count blister packs, 30-count bottles, or 120-count bottles.